Cruz Azul vs Santos Laguna Prediction, Betting Tips, Lineups & Odds

Cruz Azul vs Santos Laguna Predictions

Bet on the Underdogs to Cover the Line

We can bank some insurance on the outsiders by wagering Santos Laguna +1.25 at 1.94 on the Asian Handicap. Our money is divided between +1 and +1.5 and we’re happy to back them against Cruz Azul.

Explore our full Cruz Azul vs Santos Laguna betting preview, which features the complete write-up for our main match prediction, alongside our correct score prediction, player prop picks, corners prediction and bet builder tips.

Cruz Azul vs Santos Laguna Preview

Cruz Azul go head-to-head with Santos Laguna at Estadio Banorte, with kick-off set for 00:00 on Monday 7 September.

Cruz Azul have been handed two Liga MX home losses in a row. In their last league game, they beat Club Necaxa away by a 3-1 scoreline at Estadio Victoria. Joel Huiqui’s team enjoyed 54% possession and had eight shots on target, while Jeremy Marquez, Nicolas Ibanez and Willer Ditta scored one goal each.

Santos Laguna drew 0-0 against Tigres UANL in their previous game. This was on home soil at Estadio Nuevo Corona. The Comarca Lagunera outfit had the lion’s share of the ball boasting 59% possession and three shots on goal.

2-1 Win for Cruz Azul in Last H2H Battle

Cruz Azul have beaten Santos on four consecutive occasions. Their last clash saw Cruz Azul enjoy a 2-1 away win at Estadio Nuevo Corona. The previous 10 H2H meetings have involved five Cruz Azul wins, three Santos victories and two draws.

Cruz Azul – Last 10 League Games

Cruz Azul have 5 wins, 3 losses and 2 draws, averaging 1.7 goals from 6.0 shots on goal and 12.7 attempts. La Máquina Celeste have averaged 47.6% possession and 6.0 corners per game, with the opposition getting 1.5 goals from 3.7 shots on goal, 8.3 attempts and 4.3 corners.

Players to Watch

Top scorer Jeremy Marquez has found the net 4 times, Nicolas Ibanez 3, with Agustin Palavecino and Christian Ebere both scoring 2. Leading assistor is Carlos Rodriguez with 5.

Santos Laguna – Last 10 League Games

Santos have won 1, lost 8 and drawn 1, averaging 8.3 attempts, 2.5 shots on goal and 0.9 goals. Renato Paiva’s side average 50.4% possession, 5.9 corners in their favour and 5.1 corners against, while 1.8 goals have been conceded from 5.8 shots on goal and 12.6 attempts.

Players to Watch

Lucas Di Yorio has scored 3 goals, followed by Ezequiel Bullaude, Eduardo Aguirre, Emmanuel Echeverria and Aldo Lopez on 1. Ezequiel Bullaude has managed to clock up 3 assists in the last 10 games.

Confirmed Lineups

Cruz Azul confirmed lineup (5-3-2): Kevin Mier (GK), Willer Ditta, Amaury Garcia, Jesus Orozco, Jeremy Marquez, Omar Campos, Agustin Palavecino, Rogelio Gonzalez, Carlos Rodriguez, Nicolas Ibanez, Luka Romero.

Santos Laguna confirmed lineup (4-2-3-1): Carlos Acevedo (GK), Mauricio Cuevas, Jonathan Perez Sanchez, Felipe Sanchez, Efrain Orona, Salvador Mariscal, Aldo Lopez, Diego Gonzalez, Luis Gomez, Kevin Palacios, Ezequiel Bullaude.

Main Match Prediction

We can’t pass up the chance to wager Santos Laguna +1.25 on the Asian Handicap. Take the price of 1.94 for this Liga MX match in the expectation that the underdogs can run their opponents close.

Key stats supporting our main match prediction (league matches):

• The +1.25 line has been covered by Santos in 4 of their last 5 games.
• The +1.25 line has been covered by Santos in 7 of their last 10 games.
• The +1.25 line has been covered by Santos in 3 consecutive games.
• The -1.25 line hasn’t been covered by Cruz Azul in 6 consecutive games at home.
• The -1.25 line hasn’t been covered by Cruz Azul in 9 of their last 10 games.
• The -1.25 line hasn’t been covered by Cruz Azul in 17 of their last 20 games.
• The -1.25 line hasn’t been covered by Cruz Azul in 3 consecutive games against Santos.

Getting the lowdown on injuries and studying the Liga MX form guide are important duties ahead of making football predictions. We also place great emphasis on the stats and a data-led approach can sometimes be effective.

Santos +1.25 Probability

The betting odds at the top bookies suggest our pick carries a 51.5% chance of winning. Based on our experts research, we calculate the actual probability to be closer to 60%. That means we’re regarding it as a value bet.

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Santos Asian Hcp +1.25 @ 1.94


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Disclosure: This preview contains affiliate links; we may earn a commission at no extra cost to you. T&Cs apply. We only recommend licensed and regulated operators. See our Editorial Policy. Pick odds and lines reflect the price available at the time of publication (Sep 5, 06:27). Live market odds are updated regularly and may differ. 18+ (or legal age) | Gamble Responsibly.

Published 06:27, 05 September 2026

Player Prop Picks

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Corners Prediction

The 3.5 corners line has been covered by Santos in six consecutive matches, with Cruz Azul conceding over 3.5 corners in their past four games. There’s an opportunity to go over the Santos Team Corners line and we’re expecting this to happen, with odds of 1.98 available.

League Games

Cruz Azul

Total

10.30
6.00
4.30

Home

8.90
6.10
2.80

Away

11.30
6.10
5.20

Santos

Total

11.00
5.90
5.10

Home

10.10
5.40
4.70

Away

9.70
5.10
4.60

Latest Corner Odds

Total Corners

Cruz Azul Corners

Santos Corners

Most Corners

Pick odds and lines correct at publication. Live market odds are updated regularly and may differ. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Cruz Azul vs Santos Laguna Odds

The odds and lines below are updated regularly and may differ from the prices shown in our picks, which are captured at the time of publication.

Cruz Azul Victory on the Cards According to Betting Sites

The bookmakers take few chances with their latest odds of 1.33 for Cruz Azul winning which suggests that they have a 75% chance in this Liga MX encounter. If you want to wager on the underdog, Santos Laguna have been priced up at 7.50.

You can take advantage of the Half-Time Result market if you think a team will lead at the break. There’s the chance to back Cruz Azul at 1.67, go for Santos at 5.80 or take the draw at 2.70.

There’s a high probability that Over 2.5 Goals will be netted according to the current prices. For those expecting both sides to find the net, Both Teams to Score Yes is available at 1.58.

The best football betting sites have excellent coverage for the latest Liga MX games. They supply customers with hundreds of markets and it’s down to you to find the best angle.

Gabriel Matías Fernández Favourite to Find the Net First

Those interested in favourite Gabriel Matías Fernández to find the net first are able to get 4.10. If the Anytime Goalscorer angle makes more appeal, then this is 1.88.

Player Goals

Player Shots On Target

Live market odds and lines updated regularly. All odds subject to change. T&Cs apply. 18+ (or legal age) | Gamble Responsibly.

Estadio Banorte

Cruz Azul Have Avoided Defeat in Past Three H2H Estadio Banorte Games

Stats: Liga MX matches only
Cruz Azul have clocked up four wins, three draws and three defeats in the past 10 home games, recording an average of 1.60 goals per match and conceding 1.20.

The past six Santos Laguna games on the road have ended in defeat. The Comarca Lagunera outfit have finished with eight defeats, one win and one draw in the past 10 away matches, netting an average of 1.20 goals per game and conceding 2.80.

Cruz Azul won 3-2 when they last played Santos at Estadio Banorte. It’s been four Cruz Azul wins, two draws and two Santos victories in the past 8 H2H meetings at Estadio Banorte.

Cruz Azul Home Stats		4-3-3	2.80	1.60	1.20	6	4	6	4
Santos Laguna Away Stats		1-1-8	4.00	1.20	2.80	9	1	7	3

• W-D-L = Wins-Draws-Losses
• G = Avg. Goals
• GF = Avg. Goals For
• GA = Avg. Goals Against
• O2.5 = Matches Over 2.5 Goals
• U2.5 = Matches Under 2.5 Goals
• B-Y = Matches BTTS Yes
• B-No = Matches BTTS No

Cruz Azul vs Santos Laguna Lineups & Team News

Don’t miss the latest Cruz Azul vs Santos team news before you bet. We’ll share both predicted and confirmed lineups for the Liga MX along with the latest injury news.

Expert Analysis by Diego Sánchez

Liga MX Analyst

About the Analyst

Our football previews are produced by a specialised team of analysts, former odds compilers and sports journalists. Picks are research-driven and reviewed for accuracy and editorial consistency under the oversight of our Football Editorial Betting Panel and Editor-in-Chief.

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Liga MX Predictions Methodology

Our Liga MX analysis blends squad rotation, home altitude advantage and card/suspension trends with odds movement across both the Apertura and Clausura tournaments. We use metrics such as xG, xT and defensive efficiency indicators to assess true team strength and identify value in Mexican top-flight football.

Full Prediction Methodology & Data Sources

Sites Referenced

Betting sites, prediction market platforms and social betting sites referenced have been independently reviewed under our published review methodology, which evaluates odds and market depth, event contracts and pricing, licensing and security, payment processes, withdrawal reliability, responsible gambling tools and additional platform criteria relevant to user experience and regulatory standards.

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Transparency & Safety

This preview was last updated on Sep 6, 23:00 to reflect the latest team news, injury reports, predicted and confirmed lineups, advanced performance metrics and market movement.


All analysis is produced by professional analysts, supported by proprietary internal models, advanced performance metrics and reviewed by our Football Betting Panel for accuracy and consistency.

Historical performance for our main match predictions is tracked and updated regularly for transparency.